Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study.
Identifieur interne : 001375 ( Main/Exploration ); précédent : 001374; suivant : 001376Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study.
Auteurs : Heather E. Whitson [États-Unis] ; Alice M. Arnold [États-Unis] ; Laura M. Yee [États-Unis] ; Kenneth J. Mukamal [États-Unis] ; Jorge R. Kizer [États-Unis] ; Luc Djousse [États-Unis] ; Joachim H. Ix [États-Unis] ; David Siscovick [États-Unis] ; Russell P. Tracy ; Stephen M. Thielke [États-Unis] ; Calvin Hirsch ; Anne B. Newman [États-Unis] ; Susan Zieman [États-Unis]Source :
- The journals of gerontology. Series A, Biological sciences and medical sciences [ 1758-535X ] ; 2014.
Descripteurs français
- KwdFr :
- Activités de la vie quotidienne, Femelle, Humains, Incidence, Lysine (analogues et dérivés), Lysine (sang), Maladies cardiovasculaires (sang), Maladies cardiovasculaires (épidémiologie), Marqueurs biologiques (sang), Mâle, Personne âgée fragile, Personnes handicapées, Pronostic, Prévalence, Réadaptation cardiaque, Sujet âgé, Sujet âgé de 80 ans ou plus, Vieillissement (sang), État de santé, États-Unis d'Amérique (épidémiologie), Études de suivi, Études rétrospectives.
- MESH :
- analogues et dérivés : Lysine.
- sang : Lysine, Maladies cardiovasculaires, Marqueurs biologiques, Vieillissement.
- épidémiologie : Maladies cardiovasculaires, États-Unis d'Amérique.
- Activités de la vie quotidienne, Femelle, Humains, Incidence, Mâle, Personne âgée fragile, Personnes handicapées, Pronostic, Prévalence, Réadaptation cardiaque, Sujet âgé, Sujet âgé de 80 ans ou plus, État de santé, Études de suivi, Études rétrospectives.
English descriptors
- KwdEn :
- Activities of Daily Living, Aged, Aged, 80 and over, Aging (blood), Biomarkers (blood), Cardiac Rehabilitation, Cardiovascular Diseases (blood), Cardiovascular Diseases (epidemiology), Disabled Persons, Female, Follow-Up Studies, Frail Elderly, Health Status, Humans, Incidence, Lysine (analogs & derivatives), Lysine (blood), Male, Prevalence, Prognosis, Retrospective Studies, United States (epidemiology).
- MESH :
- chemical , analogs & derivatives : Lysine.
- chemical , blood : Biomarkers, Lysine.
- blood : Aging, Cardiovascular Diseases.
- epidemiology : Cardiovascular Diseases, United States.
- Activities of Daily Living, Aged, Aged, 80 and over, Cardiac Rehabilitation, Disabled Persons, Female, Follow-Up Studies, Frail Elderly, Health Status, Humans, Incidence, Male, Prevalence, Prognosis, Retrospective Studies.
Abstract
Advanced glycation endproducts are biologically active compounds that accumulate in disordered metabolism and normal aging. Carboxymethyl-lysine (CML), a ubiquitous human advanced glycation endproduct, has been associated with age-related conditions and mortality. Our objective was to ascertain the relationship between CML and geriatric outcomes (disability and frailty) in a large cohort of older men and women.
DOI: 10.1093/gerona/glt155
PubMed: 24127427
Affiliations:
- États-Unis
- Californie, Caroline du Nord, Maryland, Massachusetts, Pennsylvanie, Washington (État), État de New York
- Seattle
- Université de Washington
Links toward previous steps (curation, corpus...)
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Le document en format XML
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Series A, Biological sciences and medical sciences</title><idno type="eISSN">1758-535X</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Activities of Daily Living</term><term>Aged</term><term>Aged, 80 and over</term><term>Aging (blood)</term><term>Biomarkers (blood)</term><term>Cardiac Rehabilitation</term><term>Cardiovascular Diseases (blood)</term><term>Cardiovascular Diseases (epidemiology)</term><term>Disabled Persons</term><term>Female</term><term>Follow-Up Studies</term><term>Frail Elderly</term><term>Health Status</term><term>Humans</term><term>Incidence</term><term>Lysine (analogs & derivatives)</term><term>Lysine (blood)</term><term>Male</term><term>Prevalence</term><term>Prognosis</term><term>Retrospective Studies</term><term>United States (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Activités de la vie quotidienne</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Lysine (analogues et dérivés)</term><term>Lysine (sang)</term><term>Maladies cardiovasculaires (sang)</term><term>Maladies cardiovasculaires (épidémiologie)</term><term>Marqueurs biologiques (sang)</term><term>Mâle</term><term>Personne âgée fragile</term><term>Personnes handicapées</term><term>Pronostic</term><term>Prévalence</term><term>Réadaptation cardiaque</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Vieillissement (sang)</term><term>État de santé</term><term>États-Unis d'Amérique (épidémiologie)</term><term>Études de suivi</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Lysine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers</term><term>Lysine</term></keywords><keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Lysine</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Aging</term><term>Cardiovascular Diseases</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cardiovascular Diseases</term><term>United States</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Lysine</term><term>Maladies cardiovasculaires</term><term>Marqueurs biologiques</term><term>Vieillissement</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Maladies cardiovasculaires</term><term>États-Unis d'Amérique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Activities of Daily Living</term><term>Aged</term><term>Aged, 80 and over</term><term>Cardiac Rehabilitation</term><term>Disabled Persons</term><term>Female</term><term>Follow-Up Studies</term><term>Frail Elderly</term><term>Health Status</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Prevalence</term><term>Prognosis</term><term>Retrospective Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Activités de la vie quotidienne</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Mâle</term><term>Personne âgée fragile</term><term>Personnes handicapées</term><term>Pronostic</term><term>Prévalence</term><term>Réadaptation cardiaque</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>État de santé</term><term>Études de suivi</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Advanced glycation endproducts are biologically active compounds that accumulate in disordered metabolism and normal aging. Carboxymethyl-lysine (CML), a ubiquitous human advanced glycation endproduct, has been associated with age-related conditions and mortality. Our objective was to ascertain the relationship between CML and geriatric outcomes (disability and frailty) in a large cohort of older men and women.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Caroline du Nord</li><li>Maryland</li><li>Massachusetts</li><li>Pennsylvanie</li><li>Washington (État)</li><li>État de New York</li></region><settlement><li>Seattle</li></settlement><orgName><li>Université de Washington</li></orgName></list><tree><noCountry><name sortKey="Hirsch, Calvin" sort="Hirsch, Calvin" uniqKey="Hirsch C" first="Calvin" last="Hirsch">Calvin Hirsch</name><name sortKey="Tracy, Russell P" sort="Tracy, Russell P" uniqKey="Tracy R" first="Russell P" last="Tracy">Russell P. Tracy</name></noCountry><country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Whitson, Heather E" sort="Whitson, Heather E" uniqKey="Whitson H" first="Heather E" last="Whitson">Heather E. Whitson</name></region><name sortKey="Arnold, Alice M" sort="Arnold, Alice M" uniqKey="Arnold A" first="Alice M" last="Arnold">Alice M. Arnold</name><name sortKey="Djousse, Luc" sort="Djousse, Luc" uniqKey="Djousse L" first="Luc" last="Djousse">Luc Djousse</name><name sortKey="Ix, Joachim H" sort="Ix, Joachim H" uniqKey="Ix J" first="Joachim H" last="Ix">Joachim H. Ix</name><name sortKey="Kizer, Jorge R" sort="Kizer, Jorge R" uniqKey="Kizer J" first="Jorge R" last="Kizer">Jorge R. Kizer</name><name sortKey="Mukamal, Kenneth J" sort="Mukamal, Kenneth J" uniqKey="Mukamal K" first="Kenneth J" last="Mukamal">Kenneth J. Mukamal</name><name sortKey="Newman, Anne B" sort="Newman, Anne B" uniqKey="Newman A" first="Anne B" last="Newman">Anne B. Newman</name><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><name sortKey="Thielke, Stephen M" sort="Thielke, Stephen M" uniqKey="Thielke S" first="Stephen M" last="Thielke">Stephen M. Thielke</name><name sortKey="Yee, Laura M" sort="Yee, Laura M" uniqKey="Yee L" first="Laura M" last="Yee">Laura M. Yee</name><name sortKey="Zieman, Susan" sort="Zieman, Susan" uniqKey="Zieman S" first="Susan" last="Zieman">Susan Zieman</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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